TELEMERES
AND LONGEVITY
Longevity appears to be controlled
at the end of the chromosomes by a section called telomeres. The telomeres
contain subunits of DNA that initially contain about 10,000 bases at
birth that gradually decreases in length to a point where senility starts
and terminates in death.
Research has developed an agent that activates the enzyme telomerase
which is believed to increase telomere length. This agent is derived
from the root of the plant Astragalus. The condition of the telomeres
is a reflection on the status of the cells. Healthy telomere; healthy
cells. However, as cells continue to divide the telomeres get shorter.
As one reaches the 70s and 80s or develop a serious chronic disease
the telomeres will become very short ; cell division slows up and death
may soon follow.
Scientists for many years have been working with an enzyme called telomerase
in an attempt to immortalize human cells. In laboratory cultures telomerase
has been able to maintain longevity in all types of cells such as colon,
skin, retina and breast.
The hope is to possibly increase longevcity and slow down the aging
process and possibly reverse the effects of serious debilitating diseases.
The doctor and patient must evaluate the risk/benefit of using such
an agent to increase the length of telomeres. It will take many more
years of research to determine the efficacy of such treatment. The patient
who is over the age of fifty years or the very elderly facing death
might be considered potential candidates for such treatment when they
are fully informed. Younger patients faced with the onset of a serious
chronic disease (heart disease, COPD,
diabetes type 1, chronic
kidney disease, Crohn’s disease,
ulcerative colitis, Parkinson, Alzheimer’s,
ALS, multiple
sclerosis) could be also candidates for this therapy.
The medication can be taken by mouth. In some cases the patient’s
cells could be cultured with a gene for telomerase and then re-administered
into the patient for a short term therapy.
Persons interested in getting further information about telomeres/telomerase
and cost of treatment should contact us by e-mail at info@stemcellregenmed.com
or by calling 1-888-620-0411